Seems unlikely. Training was partly from human games, and partly from self play; if there's some new, off book heuristics at play, there's no way to know that humans would respond poorly to them. Though I suppose it's possible it would notice that humans do poorly on simply off book moves generally.
Why does this seem unlikely? Humans do poorly with "off book" moves in general in sports and other games; it's why new styles of play or management work really well until others get used to them. Why would it be unlikely in Go?